Investigate Stem Cell Transplantations Following Senolytic Treatment in Aged Mice

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Investigate Stem Cell Transplantations Following Senolytic Treatment in Aged Mice

SENS Connections

Intro to SENS:

Intramural Research:

A Better Way to Create Rejuvenation Therapies

A New Immune Cell Type That Can Fight Senescence

A Small Molecule Approach to Removal of Toxic Oxysterols as a Treatment For Atherosclerosis

Activated Macrophages: a New Player in Senescence-Driven Damage

Advancing Mitochondrial Health with Protective Gene Copies

Boosting Natural Defenses: Modifying Immune Cells to Target Senescence

Creation of Novel Mouse Lines to Test New Mitochondria Therapies

Harnessing Existing Medication to Target and Destroy Senescent Cells

Identification and Targeting of Noncanonical Death Resistant Cells

Mitochondrial Makeover: Replacing Old Power Sources with New

Extramural Research:

Glucosepane Crosslinks and Undoing Age-Related Tissue Damage

Harnessing Bacterial Enzymes to Dissolve the Junk Inside Aging Cells

Maximally Modifiable Mouse

New Molecules on the Frontline Battling Brain Infections and Harmful PlaqueAmylo

Remediation of Aberrant Intracellular Tau

Repairing the Brain: Engineering Cells for Cognitive Preservation

Therapy to Destroy Cells with Reactivated “Jumping Genes”

Turning Back the Clock on Tissue Stiffness and Aging

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