Extramural Research

Since our founding in 2009, the establishment and ongoing expansion of our extramural research program has been a major part of SENS Research Foundation’s commitment to changing the way the world researches and treats age-related disease. We recognize that building and sustaining collaborations throughout a global research community is crucial to the realization of our mission. Toward this end, we fund work at some of the top universities and research institutions in the world. Learn more about each active project and how it relates to SRF’s mission using the links in this section.

Ongoing Projects

Principal Investigator: Ziyu Wang

Research Team: Anthony Weiss (Co-PI), Dr. Suzanne Mithieux, Kekini Kuppan

Part of:

Principal InvestigatorAnnelise E. Barron

Research TeamKristian Sørensen, Jennifer Lin, Josefine Eilsø Nielsen, and John Fortkort

Part of:

Past Projects

Principal Investigator: Jean Hébert, PhD

Research Team: Hiroko Nobuta, Joanna Krzyspiak, Alexandra Quezada, Marta Gronska-Peski, Jayleecia Smith

Part of:

Principal Investigator: Tilman Grune, PhD

Research Team: Annett Braune, Annika Höhn, Tim Baldesperger

Part of:

Principal Investigator: Jonathan Clark, PhD

Research Team: Melanie Stammers

Part of:

Principal Investigator: Andrei Gudkov, PhD, DSci

Research Team: Marina Antoch, Amy Stablewski, Nick Neznanov, Lilya Novototskaya, Olga Leontieva

Part of:

Enhancing Innate Immune Surveillance of Senescent Cells (Fundamental Science)

Principal Investigator: Judith Campisi, PhD, Amit Sharma, PhD

Research Team: Abhijit Kale

Remediation of Aberrant Intracellular Tau

Project Director: Julie Andersen, PhD

Research Team: Cyrene Arputhasamy, Manish Chamoli, Anand Rane

The Maximally-Modifiable Mouse

Project Director: Ruby Yanru Chen-Tsai, PhD

Glucosepane Crosslinks and Undoing Age-Related Tissue Damage

Principal Investigator: David Spiegel, PhD

Research Team: Prof. Jason Crawford, Nam Kim, Venkata Sabbasani, Matthew Streeter

A Genetic Shortcut to Longevity?

Principal Investigator: Robert Shmookler-Reis

Degradation of A2E

Principal Investigators: Bruce Rittmann, Claudia Schmidt-Dannert, Janet Sparrow

Research Team: John Schloendorn, Lorenzo Albanello, Keith Causey, Brian Cook, Mark Hamalainen, David Jackemeyer, Lijing Jiang, Kent Kemmish, Daniel Kimbel, Horacio Ramirez, Justin Rebo, Jonathan Sankman, Nason Schooler, Lindsey Sherman, Lauri Tontson, Tim Webb

Epimutations: Targets or Bystanders for Rejuvenation Biotechnology?

Principal Investigator: Jan Vijg

Research Team: Xiao Dong, Sylvia Gravina

Novel Diagnostics for Transthyretin Amyloid

Principal Investigator: Brian O’Nuallain

Research Team: Adam Cantlon

Lysosomes in Macular Degeneration

Principal Investigator: Daria Mochly-Rosen

Research Team: Gouri Yogalingam

Nuclear Genes, Mitochondrial Proteins

Principal Investigator: Marisol Corral-Debrinski

Population Growth Without Aging

Principal Investigators: Leonid Gavrilov, Natasha Gavrilova

Rejuvenating the Immune System

Principal Investigator: Janko Nikolich-Zugich

Research Team: Megan Smithey

Rejuvenation of the Systemic Environment

Principal Investigator: Irina Conboy

Research Team: Keith Causey, Justin Rebo

Opportunities and Challenges of a World with Negligible Senescence

Principal Investigators: Barry Hughes, Randall Kuhn

Research Team: Eli Margolese-Malin, Dale Rothman, José Solórzano

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