Altos Labs recruits star researchers for rejuvenation therapeutics

As reported in the MIT Technology Review, the rejuvenation start-up is recruiting top researchers to work on “unfettered blue-sky research on how cells age and how to reverse that process.” Milner, a billionaire investor and science enthusiast, and Amazon founder Jeff Bezos are said to be investing in the venture that has so far brought on Juan Carlos Izpisúa Belmonte from the Salk Institute, UCLA professor Steve Horvath, and Nobel Prize winning scientist Shinya Yamanaka, who will chair the scientific advisory board.

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Senotherapeutics Report

With sponsorship from SRF, Longevity.Technology’s Market Intelligence Unit has published a report examining the potential of targeting cell senescence to treat many major diseases – particularly including current and upcoming investment opportunities – accompanied by a foreword written by SRF Chief Science Officer, Dr. Aubrey de Grey.

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PulseChain Airdrop

PulseChain Airdrop has ended! The Sacrifice Phase for the Airdrop is officially closed and all final donor information has been sent to the PulseChain team. NO changes or additions can be made at this time. The PulseChain Airdrop has ended! The PulseChain Airdrop sacrifice phase has ended. We are extremely grateful to Richard Heart and …

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Harnessing Bacterial Enzymes to Dissolve the Junk Inside Aging Cells

German Institute of Human Nutrition Principal Investigator: Tilman GruneResearch Team: Annett Braune, Annika Höhn, Tim Baldesperger Prof. Grune is the Scientific Director of the German Institute of Human Nutrition and has been working on protein degradation of damaged proteins and aging. Lipofuscin (LF) is a strongly oxidized material composed of covalently cross-linked proteins, lipids, and …

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New Breakthroughs in Clearing Out Brain Cell Plaques from the Inside

Research Info Tau is the major microtubule-associated protein (MAP) in mature neurons in the central nervous system. The MAPT (microtubule-associated protein tau) gene encodes for six splice variants that are highly soluble; their main function is interacting and stabilizing microtubules, along with other MAPs. The ability of tau to stabilize the microtubule is aided by …

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Advancing Mitochondrial Health with Protective Gene Copies

Research Info Mitochondria perform and support several vital functions in a cell, and the alternate genome, mtDNA, plays a critical role in organelle maintenance. There is increasing evidence that mitochondrial function declines with age, and that dysfunctional mitochondria adversely contribute to several metabolic and neuromuscular diseases. Our goal is to address age-acquired and inborn errors …

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A New Immune Cell Type That Can Fight Senescence

Research Info When normal cells lose their ability to replicate, they become senescent cells. Over time, senescent cells accumulate in aging tissues, spewing off a cocktail of inflammatory and growth factors, as well as enzymes that break down surrounding tissue and cause inflammation. This phenomenon is known as the “senescence-associated secretory phenotype” (SASP). Senescent cells – and …

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