COVID-19 and Aging
Why is the novel coronavirus so deadly to the elderly? We outline some of the ways in which aging is relevant to diseases like COVID-19 – and how our research may help render future viruses far less dangerous.
SRF
New 2020 Publications
2020 has already seen six new SRF-supported papers – including validation of a key tactic to prevent mitochondrial aging by our MitoSENS team, and an in-depth review coauthored by SRF, Underdog Pharmaceuticals and professor W. Gray Jerome on the major LysoSENS target 7-ketocholesterol.
SRF Publication on Mitochondrial Genome in Aging and Disease and the Future of Mitochondrial Therapeutics
We are proud to announce the publication of our review article “The Mitochondrial Genome in Aging and Disease and the Future of Mitochondrial Therapeutics” in Biomedicines, from our very own Dr. Amutha Boominathan and members at SENS.
Revel Pharmaceuticals Launched
Glucosepane crosslink breaker research graduates from top Yale lab into the biotech world Kizoo Technology Capital leads seed round financing at Revel Pharmaceuticals SAN FRANCISCO/NEW HAVEN/BERLIN, Jan. 21, 2020 — For the past 10 years, Yale Professors David Spiegel and Jason Crawford have been working on tools to enable the development of glucosepane-cleaving drugs. Kizoo …
Underdog Pharmaceuticals Launched
Novel therapeutic approach to cardiovascular disease from SENS Research Foundation flagship research program graduates from laboratory to the biotech world Kizoo Technology Capital leads seed round financing at Underdog Pharmaceuticals SRF announces leadership appointments MOUNTAIN VIEW, Calif., Nov. 14, 2019 (GLOBE NEWSWIRE) — Underdog Pharmaceuticals, Inc. (Underdog), and SENS Research Foundation (SRF) today announced the …
Staging Aging
A team including SRF protégé Stuart Calimport and several members of our Research Advisory Board argues in Science that the systematic classification and staging of aging-related pathology (as is currently done for cancer) should dramatically accelerate the deployment of rejuvenation therapies.
Identification and Targeting of Noncanonical Death Resistant Cells
SENS Research Foundation Research Center Forever Healthy Foundation Fellowship in Rejuvenation Biotechnology Fellow: Tesfahun Admasu When cells age, they lose their proliferative capacity and stop dividing in a phenomenon called senescence. Cellular senescence decreases the regenerative capacity of cells and tissues. Throughout the aging process, senescent cells accumulate and secrete a characteristic set of proteins, called …
Job Opportunity: Research Assistant (Immunology)
We are seeking a full-time Research Assistant to join the Senescence Immunology group at our Research Center in Mountain View, CA, for a project geared toward developing therapies to restore the ability of the aging immune system to clear senescent cells.
MitoMouse Project
Work supported by the 2015 MitoSENS crowdfunding initiative demonstrated that our strategy to neutralise mitochondrial mutations works in cell culture. Now, our new MitoMouse project aims to prove that the same technique can work in live mice. Can you help us raise the $50,000 we need?
Rejuvenation Now!
The Forever Healthy Foundation has launched a new “Rejuvenation Now” initiative, designed to identify rejuvenation therapies that are available right now and evaluate their risks and benefits. Analyses of NAD+ Restoration Therapy and Fisetin Senolytic Therapy are now available to read.
