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Therapeutic application of cardiac stem cells and other cell types.
Hayashi E, Hosoda T
Abstract:
.....So far skeletal myoblasts, bone marrow-derived cells, mesenchymal stromal cells, and resident cardiac cells have been applied for therapeutic myocardial regeneration. Among them, autologous transplantation of c-kit-positive cardiac stem cells in congestive heart failure patients resulted in an outstanding outcome, with long-lasting beneficial effects without major adverse events. By reviewing these clinical trials, an endeavor was made to seek for an ideal cellular therapy for cardiovascular diseases.
PMID: 23878816
Free Full-Text: http://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23878816/
