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Neural stem cells harvested from live brains by antibody-conjugated magnetic nanoparticles.
Lui CN, Tsui YP, Ho AS, Shum DK, Chan YS, Wu CT, Li HW, Tsang SC, Yung KK
Abstract:
.....The extraction of stem/progenitor cells from the brain of live animals is possible using antibodies conjugated to magnetic nanoparticles (Ab-MNPs). The Ab-MNPs are introduced to a rat's brain with a superfine micro-syringe. The stem cells attach to the Ab-MNPs and are magnetically isolated and removed. They can develop into neurospheres and differentiate into different types of cells outside the subject body. The rat remains alive and healthy.
