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Mitochondria DNA 4977 bp common deletion in peripheral whole blood from healthy donors.
Biomed Environ Sci. 2013 Dec;26(12):990-3. doi: 10.3967/bes2013.035
Wang P, Liu YL, Han L, Zhao FL, Guo F, Wang XA, Lv YM
Abstract:
To investigate the distribution of mitochondria DNA 4 977 bp deletion, a common deletion (CD), in normal populations of Chinese, human peripheral blood samples from sixty healthy donors were collected, and levels of the CD in genomic DNA from the samples were detected using real-time PCR.
The results showed that the CD was found in 27 health donors, with its positive rate being 45% (27/60). The CD ratio was between 0 and 0.00308%, and not affected by age and gender in sixty healthy donors
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The results showed that the CD was found in 27 health donors, with its positive rate being 45% (27/60). The CD ratio was between 0 and 0.00308%, and not affected by age and gender in sixty healthy donors
.....
PMID: 24393509
Tags: 4, 977 bp deletion, mtDNA