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Intracellular observation of nanocarriers modified with a mitochondrial targeting signal peptide.
J Biosci Bioeng. 2013 Jun 1. pii: S1389-1723(13)00164-3. doi: 10.1016/j.jbiosc.2013.05.001
Kawamura E, Yamada Y, Yasuzaki Y, Hyodo M, Harashima H
Abstract:
This study focused on the intracellular observation of nanocarriers modified with a mitochondrial targeting signal peptide (MTS). The nanocarriers showed an efficient cellular uptake, and the MTS had a positive effect on their mitochondrial targeting. This is the first report of an intracellular observation of nanocarriers modified with MTS.