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Human embryonic stem cell applications for retinal degenerations.
Exp Eye Res. 2013 Jul 20. pii: S0014-4835(13)00200-5. doi: 10.1016/j.exer.2013.07.010
Reynolds J, Lamba DA
Abstract:
.....The author's intent for this review is to provide an historical overview of the field of embryonic stem cells with relation to the retina. The review will provide a quick primer on key pathways involved in the development of the neural retina and RPE followed by a discussion of the various protocols out in the literature for generating these cells from non-human and human embryonic stem cells and end with in vivo application of ES cell-derived photoreceptors and RPE cells.
PMID: 23880530
Tags: AMD, retinal rejuvenation, review, RPE cells, stem cells