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Extracellular matrix alterations in senescent cells and their significance in tissue homeostasis.
Matrix Biol. 2019 Jan;75-76:27-42. doi: 10.1016/j.matbio.2017.10.004
Mavrogonatou E, Pratsinis H, Papadopoulou A, Karamanos NK, Kletsas D
Abstract:
...In this review we present the current knowledge on extracellular matrix alterations associated with cellular senescence and critically discuss certain characteristic examples, highlighting the ambiguous role of senescent cells in the homeostasis of various tissues under both normal and pathologic conditions.