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Effectiveness of bortezomib in cardiac Al amyloidosis: a report of two cases.
Case Rep Med. 2014;2014:627474. doi: 10.1155/2014/627474
Nigrelli S, Curciarello G, Ballo P, Michelassi S, Pizzarelli F
Abstract:
.....Herein we report on two patients with cardiac amyloidosis treated by bortezomib who experienced partial or total remission of hematologic disease and of cardiac involvement. However, death of one patient, suffering from chronic kidney disease stage 5, due to fulminant respiratory syndrome suggests the need for caution in bortezomib use if patients have this comorbid condition.
PMID: 24715916
Free Full-Text: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970246/
Tags: AL amyloidosis, bortezomib