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DNA-fueled molecular machine for label-free and non-enzymatic ultrasensitive detection of telomerase activity.
Analyst. 2016 Aug 2;141(16):4855-8. doi: 10.1039/c6an00997b
Sun P, Ran X, Liu C, Liu C, Pu F, Ren J, Qu X
Abstract:
Herein, a non-enzymatic and label-free strategy based on DNA-fueled molecular machine was developed for ultrasensitive detection of telomerase activity in cancer cell extracts even at the single-cell level.
PMID: 27405851
Tags: ALT, methods, telomerase