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Allotopic Expression of ATP6 in Mouse as a Transgenic Model of Mitochondrial Disease
Methods Mol Bio. 2021;2277:1-13. doi: 10.1007/978-1-0716-1270-5_1.
David A Dunn 1, Carl A Pinkert 2
Abstract:
...Here, we use our AE (allotopic expression) approach to transgenic mouse modeling of the pathogenic human T8993G mutation in mtATP6 as a case study for designing AE animal models.
PMID: 34080141
Tags: allotopic expression, animal models, ATP6, methods, mice