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A near-infrared fluorescent nanoprobe for senescence-associated β-galactosidase sensing in living cells
Chem Commun (Camb). 2023 Feb 21. doi: 10.1039/d2cc05550c.
Ye Zhao 1, Shan Sun 2, Yan Lyu 1, Mengyao Gao 1, Hengwei Lin 1 2, Cheng Yang 1
Abstract:
A near-infrared fluorescent nanoprobe based on semiconducting polymer nanoparticles (SPNs) for the detection of senescence-associated β-gal (SA-β-gal) is developed. Benefiting from the intrinsic lysosome-locating feature, this probe can be successfully used for the visualization of SA-β-gal in living cells.
PMID: 36807350
Tags: beta-galactosidase, methods, Visualization