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A cyanobenzo[a]phenoxazine-based near infrared lysosome-tracker for in cellulo imaging.
Sun R, Liu W, Xu YJ, Lu JM, Ge JF, Ihara M
Abstract:
A cyanobenzo[a]phenoxazine-based pH probe with pKa = 5.0 exhibits OFF-ON emission at 625-850 nm upon excitation at 600 nm in aqueous buffers. The in cellulo imaging experiments with HeLa cells indicate that the probe can serve as a lysosome-specific probe under red light excitation (633 nm) with near infrared emission (650-790 nm).
PMID: 24100849
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