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Age-related Impairment of Vascular Structure and Functions.
Aging Dis. 2017 Oct 1;8(5):590-610. doi: 10.14336/AD.2017.0430
Xu X, Wang B, Ren C, Hu J, Greenberg DA, Chen T, Xie L, Jin K
Abstract:
Among age-related diseases, cardiovascular and cerebrovascular diseases are major causes of death. Vascular dysfunction is a key characteristic of these diseases wherein age is an independent and essential risk factor. The present work will review morphological alterations of aging vessels in-depth, which includes the discussion of age-related microvessel loss and changes to vasculature involving the capillary basement membrane, intima, media, and adventitia as well as the accompanying vascular dysfunctions arising from these alterations.
PMID: 28966804
Free Full-Text: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614324/