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The role of oxysterols in vascular ageing.
Gargiulo S, Gamba P, Testa G, Leonarduzzi G, Poli G
Abstract:
.....This review provides an updated analysis of the molecular mechanisms whereby oxysterols accumulating in the wall of ageing blood vessels may 'activate' endothelial and monocytic cells, through expression of an inflammatory phenotype, and 'convince' smooth muscle cells to proliferate, migrate and, above all, to act as fibroblast-like cells.
PMID: 26648329
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