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Myeloid-derived suppressor cells, age and cancer.
Bowdish DM
Abstract:
We have recently discovered that the levels of circulating myeloid-derived suppressor cells, which are associated with an impaired T-cell proliferation and produce high amounts of reactive oxygen species, increase with age and are elevated in individuals in remission from cancer. Herein, potential mechanisms underpinning these observations are discussed.
PMID: 24073368
Free Full-Text: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782016/
