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Single-particle tracking for studying the dynamic properties of genomic regions in live cells.
Berger IB, Kepten E, Garini Y
Abstract:
.....Here we describe single-particle tracking which is a powerful method that allows the characterization of dynamic processes on the single-molecule or single-particle level with nanometer spatial and sub-second temporal precision. In particular, we describe the cell preparation procedures, microscopy imaging, and image analysis processes for following telomere dynamics in living mammalian cells.
PMID: 23980005
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