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Role of reactive oxygen species in the defective regeneration seen in aging muscle.
Vasilaki A, Jackson MJ
Abstract:
.....The aim of this review is to summarise the evidence that abnormal reactive oxygen species (ROS) generation in nerve and/or muscle may be responsible for the defective regeneration that contributes to the degeneration of skeletal muscle observed during aging. Identifying the importance of ROS generation in skeletal muscle during aging could have fundamental implications for interventions to prevent muscle degeneration and treatments to reverse the age-related decline in muscle mass and function.
PMID: 23851030
SENS Approach:
