NIA Reports Senolytics Show Potential to Protect Against Coronavirus in Older Mice

The NIA reports: “Cellular senescence, an aging mechanism in which cells lose normal function, may contribute to a worse response in human cells to COVID-19 and in older mice to a similar coronavirus — but a class of drug known as senolytics decreased adverse responses and increased survival for the mice. The preclinical findings from a study funded in part by NIA were recently published in Science.”

This is also the focus of one of SRF’s projects that is working on selectively removing senescent cells and reversing the damage caused by them to rejuvenate the immune system.

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