April 8, 2010 - SENS Research Foundation

Zscan4: The Possible Basis of ALT

June 14, 2022April 8, 2010 by Michael Rae

In addition to telomerase, some cancer cells become immortalised via the phenomenon known as ALT (“Alternative Lengthening of Telomeres”). A new paper published in Nature suggests that Zscan4, a gene essential for telomere maintenance in embryonic stem cells, may be the driver of the ALT mechanism.

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Zscan4: The Possible Basis of ALT

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