Iron in Aging and Neurodegenerative Disease

Ashley Bush, Head of the Oxidation Disorders Laboratory, Mental Health Research Institute, University of Melbourne; Director of the Laboratory for Oxidation Biology Genetics and Aging Unit, Massachusetts General Hospital; Associate Professor, Department of Psychiatry, Harvard Medical School

Video Overview

Ashley I. Bush (MB BS, DPM, FRANZCP, PhD, FTSE) heads the Oxidation Biology Unit at the Florey Institute of Neuroscience & Mental Health, is Professor of Neuroscience and Pathology at The University of Melbourne, NHMRC Australia Fellow, co-director of biomarker development for the Australian Imaging Biomarker Lifestyle Study (AIBL), Chief Scientific Officer of the Cooperative Research Center for Mental Health, and has staff appointments in Psychiatry and Radiology at the Massachusetts General Hospital.

He has received numerous awards including the Potamkin Prize and the Beeson Award. Professor Bush has authored over 300 publications, with over 21,000 citations (the most highly-cited Australian neuroscientist of the last 10 years), 23 patents and founded 4 biotechnology companies. His lab discovered the interaction of beta-amyloid with transitional metals as a major factor in Alzheimer’s disease pathology, as well as the roles of APP and tau in neuronal iron homeostasis.