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The cerebellum in Parkinson’s disease.
Brain. 2013 Mar;136(Pt 3):696-709. doi: 10.1093/brain/aws360
Wu T, Hallett M
Abstract:
Parkinson's disease is a chronic progressive neurodegenerative disorder characterized by resting tremor, slowness of movements, rigidity, gait disturbance and postural instability. Most investigations on Parkinson's disease focused on the basal ganglia, whereas the cerebellum has often been overlooked. However, increasing evidence suggests that the cerebellum may have certain roles in the pathophysiology of Parkinson's disease. Anatomical studies identified reciprocal connections between the basal ganglia and cerebellum. [FULL]: " Here, we review related anatomical, clinical and neurophysiological findings, and discuss the possible roles of the cerebellum in the pathophysiology of Parkinson’s disease."
PMID: 23404337
Tags: parkinson's, review