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Proteopathic lesions in the brain of a super-aged chimpanzee (Pan troglodytes)
J Med Primatol. 2021 Jun 7. doi: 10.1111/jmp.12530.
Susumu Iwaide 1, Tokuma Yanai 2, Tomoaki Murakami 1
Abstract:
The brain of a chimpanzee estimated to be 68 years old, the oldest reported so far, has been examined. Pathological analyses revealed the formation of mild tau-positive neuritic clusters and cytoplasmic α-synuclein aggregates, in addition to severe cerebral amyloid angiopathy and diffuse plaques, but no tangle lesions were observed.