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C. elegans survivors without telomerase.
Worm. 2013 Jan 1;2(1):e21073. doi: 10.4161/worm.21073
Lackner DH, Karlseder J
Abstract:
.....To date, ALT and ALT-like mechanisms have only been described in the context of individual cells such as cancer cells and yeast. Now, several "survivor" strains of the nematode Caenorhabditis elegans have been generated that can propagate despite mutations of the telomerase gene. These nematode strains represent the first multi-cellular organism with canonical telomerase that can survive in the absence of a functional telomerase pathway.
PMID: 24058854
Free Full-Text: http://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24058854/
Tags: ALT, animal models