External News Archive

Have scientists found the 'Elixir of Youth'? Gene that destroys unhealthy cells is found to extend the life of flies by more than 60%

"Scientists may have hit upon a new way of extending the lifespan of living organisms - by activating a gene that destroys unhealthy cells. Researchers at the University of Bern found they were able to help flies live up to 60% longer by increasing the activity of a gene that targets damaged cells. If this could be transferred to humans, it could extend the average lifespan of people in developed countries like the US and the UK to beyond 120 years old."

Read More at Gene that destroys unhealthy cells found to extend the life of flies by 60 per cent.

Live for ever: Scientists say they’ll soon extend life ‘well beyond 120’

"Fixing the ‘problem’ of ageing is the mission of Silicon Valley, where billions is pouring into biotech firms working to ‘hack the code’ of life – despite concerns about the social implications."

Read More at Live for ever: Scientists say they’ll soon extend life ‘well beyond 120’.

Could a 200-year-old whale offer clues to help humans live longer?

Joao Pedro de Magalhaes and his team at the University of Liverpool sequenced the genome of the bowhead whale, the longest living mammal on earth. The team wanted to understand why they live so long and don't succumb to some of the same illnesses as humans do earlier in life.

Aubrey de Grey, the SENS Research Foundation's chief science officer and one of the leading voices on extending human life, said the "biology of aging badly needs studies like this."

"The field was revolutionised over 20 years ago when mutations were discovered that greatly postpone aging by emulating the metabolic response to famine, but that avenue has not delivered as much medical progress as hoped, and many of us are now pessimistic that it ever will," de Grey said. "Therefore, it is of high priority to look in other ways for simple genetic variations that underlie differences in longevity, and the approach taken by (co-author Michael) Keane et al. is among the most promising."

Read More at Could a 200-year-old whale offer clues to help humans live longer?.

From SENS Research Foundation: Bold Leaps Forward for α-Synuclein Immunotherapy

Bold Leaps Forward for α-Synuclein Immunotherapy” is an extensive review of efforts to recruit the immune system to clear “Lewy bodies (LB) and other intracellular α-synuclein (AS) aggregates” from the brain...

Read More at From SENS Research Foundation: Bold Leaps Forward for α-Synuclein Immunotherapy.

Do you really want to live to 1,000?

"Aubrey de Grey, SENS Foundation co-founder, provides insight into regenerative medicine and longevity benefits." Short interview on CNBC.

Read More at Do you really want to live to 1,000?.

Q & A with SENS Research Foundation President, CEO and Co-Founder Michael Kope

SENS Research Foundation is a partner of the Alliance for Aging Research's Healthspan Campaign. In this interview, SRF CEO Mike Kope discusses the Foundation's work and its implications for healthy human lifespans.

Read More at Q & A with SENS Research Foundation President, CEO and Co-Founder Michael Kope.

Notes from Rejuvenation Biotech Conference

RB2014 delegate Josh Mitteldorf shares his thoughts on a number of the talks in this extended review.

Read More at Notes from Rejuvenation Biotech Conference.

RB2014: An Anti-Aging Conference

"There was a time – only a few years ago – when serious research into radical life extension was popularly considered to be completely insane. But the scientific grounds for thinking of aging as an unconquerable problem are evaporating quickly. There is no law of biology stating: “Humans shall not exceed the age of 120.” Instead, it is becoming clear that what holds back anti-aging research is institutional support, and thus: funding, laboratories, dedicated research teams, and so forth."

Read More at RB2014: An Anti-Aging Conference.

SENS Rejuvenation Biotechnology Conference

"The smell of coffee, and sounds of familiar voices permeated the air as I approached the registration desk for the SENS Rejuvenation Biotechnology Conference in Santa Clara. Friendly faces and friends greet me, and I am reminded of at time almost exactly a year ago, when I attended SENS6 in Cambridge. I am directed to the breakfast area, where over a hundred individuals gather to catch up since they last saw each other."

Read More at SENS Rejuvenation Biotechnology Conference.

This Is So Today: SENS Foundation Kicks Off New Conference on Aging

"Last week the SENS Foundation put on the first ever Rejuvenation Biotechnology conference in Santa Clara. (“Rejuvenation” might be misleading. This is a conference on aging, not on spa treatments.) The SENS Foundation operates on the “belief that a world free of age-related disease is possible,” and the conference is a way to build a community around that belief."

Read More at This Is So Today: SENS Foundation Kicks Off New Conference on Aging.

Of seismic waves and closing days: take home messages

"There were two momentous events on the night of August 23, 2014. First, the inaugural Rejuvenation Biotechnology conference drew to a close. Second, the largest earthquake in nearly 25 years hit the San Francisco Bay Area."

Read More at Of seismic waves and closing days: take home messages.

Explosive growth in cell therapy just around the corner?

"Assume a single bacterium weighs one thousand billionth of a gram. If it, and each of its progeny, divides once every 20 minutes then the population will reach approximately 4000 times the mass of the earth in two days. Such is the power of exponential change."

Read More at Explosive growth in cell therapy just around the corner?.

Life, death and regulation

"Consider this question: if I gave you the option to take a drug offering a 100 percent chance of survival to average life expectancy at which time you would certainly fall down dead, would you take it? Let’s say that age is 82. The other option is to take your chances and live to some undetermined point on a wider distribution around that age; you might only live to 60, you might live to 100, or you might fall somewhere in between."

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CRISPR and Rejuvenation Biotechnology: have you been hiding under a rock?

"‘Bay Area biotechnology’ is a description that conjures images of the proud Hoover Tower at Stanford, and the iconic Genentech sign marking “Birthplace of Biotechnology,” set against the backdrop of lingering Californian sunsets. One is unlikely to reflect on the imposing silhouette of the Levi Stadium in San Jose; however, this may be about to change."

Read More at CRISPR and Rejuvenation Biotechnology: have you been hiding under a rock?.

The Big Breakthrough in Rejuvenative Medicine

"Newly targeted immune therapies soon may enable clinicians to treat very large patient populations to whom they've had very little to offer before. But researchers can envision even more breathtaking advances in personalized care."

Read More at The Big Breakthrough in Rejuvenative Medicine.

About time: The Imagine Science Film Festival brings science to the people

"ISFF seems to embrace aging as a sub-theme of the festival itself. This year’s kickoff event featured a discussion of the science of art and time by a number of panelists, including Dr. Aubrey de Grey — the Chief Science Officer of SENS Research Foundation, which is working to find a solution to aging. De Grey, who has called the mainstream attitude towards getting old a “pro-aging trance,” was joined by Rachel Sussman, a visual artist whose most recent project is a vast photo essay of the world’s oldest living organisms."

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Aubrey de Grey: Longer lives won’t mean overpopulation

"Aubrey de Grey wants to save lives. He wants to save as many as he possibly can, as soon as he can, and to do it he is going to fix ageing.

The prominent scientist and futurologist is on a crusade to beat ageing and when he does it will mean that we stay healthy and live longer – possibly for up to hundreds of years.

But, as de Grey emphasises, his primary goal is not just making people live longer; he wants us to live healthily, he wants to restore us to a state of health that is “fully functional in every way”. The ability to live for hundreds of years is just a side effect."

Read More at Aubrey de Grey: Longer lives won’t mean overpopulation.

This Is So Today: SENS Foundation Kicks Off New Conference on Aging

"Last week the SENS Foundation put on the first ever Rejuvenation Biotechnology conference in Santa Clara.  (“Rejuvenation” might be misleading.  This is a conference on aging, not on spa treatments.)  The SENS Foundation operates on the  “belief that a world free of age-related disease is possible,”  and the conference is a way to build a community around that belief."

Read More at This Is So Today: SENS Foundation Kicks Off New Conference on Aging.

The Story of Aubrey de Grey and How the Study of Aging Became Mainstream

"Gerontology, or the study of aging, was a “backwater” science when Aubrey de Grey began his career. Today there are well financed companies with the word "longevity" in the name (i.e., Craig Venter’s latest project).

Today we bring you the story of Aubrey de Grey—scientist, author, provocateur—and how he became one of the world’s leading gerontologists. Currently CSO of the SENS Research Foundation, Aubrey tells how he went from working in artificial intelligence to the leader of a new movement in biology. Thrilled that the research community has “come to him,” Aubrey finishes the interview by explaining some of the challenges he faces today."

Read More at The Story of Aubrey de Grey and How the Study of Aging Became Mainstream.