External News Archive
"When 116-year-old Gertrude Weaver died of pneumonia this week in Arkansas, she had held the title of world’s oldest person for all of five days. And she was still a bit younger than 122-year-old Frenchwoman Jeanne Calment, who passed away in 1979 and holds the record for oldest human...
Futurists like Aubrey DeGrey have said that eliminating just a few diseases and coming up with new treatments for aging could lead to 1,000-year-old humans. DeGrey, who has been pushing his ideas on rejuvenation and life-extension, has gotten some deep-pocketed company in the past year."Read More at Will Humans Ever Live 200 Years?.
"The event has a line-up of over 40 speakers, including some of the world’s leading experts and commentators in their respective fields, who will examine and discuss the growing global challenges facing the re/insurance and captive industry and in particular its impact on managing risk.
Among the speakers secured for the event is Dr Aubrey de Grey, chief science officer at SENS Research Foundation and Prof Ian Goldin, professor of globalisation and development and director of the Oxford Martin School at the University of Oxford."Read More at European Insurance Forum details announced.
"For centuries, explorers have searched the world for the fountain of youth. Today’s billionaires believe they can create it, using technology and data."Read More at Tech titans’ latest project: Defy death.
"Cellular immortality is a hallmark of cancers that distinguishes them from normal tissue. Every time a normal somatic cell divides, the DNA at the ends of its chromosomes, called the telomeres, gets shorter. When the telomeres shorten too much, an alarm signal is generated, and the cell permanently stops dividing and enters senescence or undergoes apoptosis. Telomere shortening thus acts as a biological mechanism for limiting cellular life span. Cancer cells, on the other hand, can become immortalized by activating a telomere maintenance mechanism (TMM) that counteracts telomere shortening by synthesizing new telomeric DNA from either an RNA template using the enzyme telomerase or a DNA template using a mechanism called alternative lengthening of telomeres (ALT)."Read More at Control ALT, Delete Cancer.
"Aubrey de Grey is a true frontiersman, daring to push out against what seems the most natural and unstoppable forces of nature - ageing. He's not just another voice though, he's a scientist and identifies ageing as a disease, one that can be cured with the right medicine. His work calls for serious scientific exploration of what causes tissue to age and to then find solutions to those components - what he calls the roadmap to defeat biological ageing. In fact, he believes that the first humans who will live to be 1,000 years old are already alive today!"Read More at A Long Interview with Aubrey de Grey on London Real.
"Peter Thiel, the billionaire co-founder of PayPal, plans to live to be 120. Compared with some other tech billionaires, he doesn’t seem particularly ambitious. Dmitry Itskov, the “godfather” of the Russian Internet, says his goal is to live to 10,000; Larry Ellison, co-founder of Oracle, finds the notion of accepting mortality “incomprehensible,” and Sergey Brin, co-founder of Google, hopes to someday “cure death.”
These titans of tech aren’t being ridiculous, or even vainglorious; their quests are based on real, emerging science that could fundamentally change what we know about life and about death."Read More at Silicon Valley Is Trying to Make Humans Immortal—and Finding Some Success.
"Death—that was so last century. Here in the early 21st, it’s all about life. More life. A lot more life.
Right now, anti-aging medicine is booming. For certain, the size of the market is a little hard to determine, but most estimates put it close to $300 billion. And growing.
Already, serious heavyweights like Google and Human Longevity Inc. (HLI)—the company founded by X Prize founder Peter Diamandis, stem-cell pioneer Robert Hariri, and genomics visionary Craig Venter—have entered the fray. And, of course, ideas about slowing the insults of time are everywhere."Read More at Are We Hunting Longevity In All The Wrong Places?.
"You already know that, as we grow older, we become more prone to many kinds of ailments: cancers, heart disease, dementia, and others. Any number of private foundations are sponsoring research targeting one or more of these age-related conditions. Less common, though, are foundations that are taking on the aging process itself.
The Larry Ellison Medical Foundation used to be a leader in this area, but pulled the plug on such research in late 2013...
But Ellison was never alone in his "war on death." And two funders still searching for a modern-day fountain of youth are the Methuselah Foundation and the SENS Research Foundation. Indeed, they are partnering on finding treatments that basically make older people young again. "Read More at To These Foundations, Aging is the Enemy.
"Longevity is a subject close to my heart, and I’ve been following the career of today’s guest for many years. Dr. Aubrey de Grey is a visionary and general strategist in the field of gerontology who applies the concepts of planning, investment, and risk management to the science of aging. With his strategic approach, he’s created the seven “Strategies for Engineered Negligible Senescence” that offer a practical route to longer life.
Dr. de Grey may be the greatest activist for longevity of our time. He’s the Chief Science Officer for the SENS Research Foundation, a not-for-profit organization funding research into longevity around the world. He’s authored two books; Ending Aging: The Rejuvenation Breakthroughs that Could Reverse Human Aging in our Lifetime in 2008 and The Mitochondrial Free-Radical Theory of Aging, for which he received his PhD in 1999.
In today’s interview we examine popular longevity strategies such as caloric restriction and telomerase therapies, as well as those stemming from his research. His contrasting viewpoints offer insight compared to what you might see in the press."Read More at A Framework to Increase Longevity and End Aging.
"SENS Research Foundation is one of the few organizations persistently finding ways to move the needle, to speed things up, to bring more attention to the field. The scope of success here is at present only limited by funding: there are any number of scientists in the aging research community who would drop their present work in favor of SENS biotechnology to treat aging given the budget.
With that in mind, here is a little news for those who might have a few bitcoins left over after all the excitement of the past eighteen months or so..."Read More at SENS Research Foundation Now Accepts Bitcoin Donations.
"Age defiance is a staggeringly lucrative industry. Last year the global anti-ageing market generated more than $280 billion. By 2018 it will hit $400 billion. A new tribe is taking advantage of sophisticated scientific breakthroughs... this appears to be only the beginning of the new age of ageing. It’s little wonder that the latest venture from Google, the most successful innovator on the planet, is ageing-related. Mere cosmetic enhancements are child’s play to Google, which is on an altogether more ambitious trajectory...
Larry Ellison, CEO of the computer tech company Oracle and the fifth wealthiest man in the world, according to Forbes magazine, is the money behind the Ellison Medical Foundation, an anti-ageing biomedical research centre. The Californian venture capitalist Paul F. Glenn has endowed hundreds of millions to life-expansion research at Ivy League institutions such as Harvard, Princeton, MIT and Stanford. Peter Thiel, co-founder of PayPal and a Facebook board member, is a supporter of SENS, a research foundation specialising in rejuvenation treatments.
SENS is run by Aubrey de Grey, a British gerontologist who believes that the first person to live to 150 is already alive today – a view shared by federal treasurer Joe Hockey, who was ridiculed recently for making this exact claim while arguing the case for budget cuts.
“Rejuvenation biotechnologies are, very simply, medicines that restore the structure of the body to how it was in early adulthood, and thereby restore it to maximum physical and mental performance,” explains de Grey, who also co-founded the Methuselah – a foundation whose aim, through tissue engineering and regenerative medicine, is to create a world by 2030 in which 90-year-olds can be as healthy as 50-year-olds. “By restoring the molecular and cellular structure of the body to that of a young adult, we will necessarily restore its function, too, which constitutes reversing ageing. Thus, people will remain truly healthy for longer, postponing the ill health that inescapably accompanies old age today.”"Read More at Living to 150 is the new holy grail.
"Most people know that healthcare has rapidly become an information technology and health and medicine is changing exponentially.Just as technology is democratizing all aspects of life, no field is being disrupted more quickly than healthcare and the implications of digital will bring a trillion dollars worth of disruption to outdated diagnosis, treatment and delivery of healthcare. Moreover, the human race will live long enough soon to live forever as nanotechnology, robotics, Gene sequencing and AI cure age old problems."
Interview with SRF CSO Dr. Aubrey de Grey, Dr. Dan Barry, and Vinod Khosla.Read More at Exponential Medicine and Digital Healthcare.
Last month at the World Stem Cell Summit in San Antonio, TX, GEN’s editor-in-chief John Sterling moderated a panel discussion on “Regeneration Medicine: A New Era of Discovery and Innovation.” The following Q&A is based on some of the responses of several panel members.Read More at How to Best Hinder or Halt the Aging Process: A Roundtable Discussion on Regenerative Medicine.
"New scientific research on healing the body from within, may revolutionise the way we age, says Áilín Quinlan.
YOUTH may be wasted on the young, but it’s the holy grail for the ageing affluent. No longer willing to undergo an invasive nip-and-tuck, informed women are looking to the latest developments in science, which take an inside-out approach to ageing.
There’s a booming market in sophisticated anti-ageing procedures and products. Last year, the global market was worth €193bn. By 2018, that’s scheduled to be €280bn.
The research is being driven by some of the best scientific and business brains."Read More at Can we outface ageing?.
Have scientists found the 'Elixir of Youth'? Gene that destroys unhealthy cells is found to extend the life of flies by more than 60%
"Scientists may have hit upon a new way of extending the lifespan of living organisms - by activating a gene that destroys unhealthy cells. Researchers at the University of Bern found they were able to help flies live up to 60% longer by increasing the activity of a gene that targets damaged cells. If this could be transferred to humans, it could extend the average lifespan of people in developed countries like the US and the UK to beyond 120 years old."Read More at Gene that destroys unhealthy cells found to extend the life of flies by 60 per cent.
"Fixing the ‘problem’ of ageing is the mission of Silicon Valley, where billions is pouring into biotech firms working to ‘hack the code’ of life – despite concerns about the social implications."Read More at Live for ever: Scientists say they’ll soon extend life ‘well beyond 120’.
Joao Pedro de Magalhaes and his team at the University of Liverpool sequenced the genome of the bowhead whale, the longest living mammal on earth. The team wanted to understand why they live so long and don't succumb to some of the same illnesses as humans do earlier in life.
Aubrey de Grey, the SENS Research Foundation's chief science officer and one of the leading voices on extending human life, said the "biology of aging badly needs studies like this."
"The field was revolutionised over 20 years ago when mutations were discovered that greatly postpone aging by emulating the metabolic response to famine, but that avenue has not delivered as much medical progress as hoped, and many of us are now pessimistic that it ever will," de Grey said. "Therefore, it is of high priority to look in other ways for simple genetic variations that underlie differences in longevity, and the approach taken by (co-author Michael) Keane et al. is among the most promising."Read More at Could a 200-year-old whale offer clues to help humans live longer?.
“Bold Leaps Forward for α-Synuclein Immunotherapy” is an extensive review of efforts to recruit the immune system to clear “Lewy bodies (LB) and other intracellular α-synuclein (AS) aggregates” from the brain...Read More at From SENS Research Foundation: Bold Leaps Forward for α-Synuclein Immunotherapy.
"Aubrey de Grey, SENS Foundation co-founder, provides insight into regenerative medicine and longevity benefits." Short interview on CNBC.Read More at Do you really want to live to 1,000?.
SENS Research Foundation is a partner of the Alliance for Aging Research's Healthspan Campaign. In this interview, SRF CEO Mike Kope discusses the Foundation's work and its implications for healthy human lifespans.Read More at Q & A with SENS Research Foundation President, CEO and Co-Founder Michael Kope.